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Information from a medical drug-drug interaction research study involving montelukast and also gemfibrozil (an inhibitor of both CYP 2C8 as well as 2C9) showed that gemfibrozil, at a therapeutic dosage, raised the wide spread direct exposure of montelukast by 4. Pains in the stomach, side, or abdomen, possibly moving to the back. While the dose of inhaled corticosteroid may be reduced progressively under clinical guidance, Singulair needs to not be abruptly alternatived to inhaled or dental corticosteroids. 8 out of 5 stars The patent was filed in 1996, two years before Singulair’s approval to treat allergies and asthma in 1998. Anxiety is a feeling of apprehension and fear characterized by symptoms such as trouble concentrating, headaches, sleep problems, and irritability. Treatment for anxiety may incorporate medications and psychotherapy Singulair ( montelukast) and Claritin (loratadine) are used to treat allergy symptoms. 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